研究業績
2023年度
- Ariyasu, S., Yonemura, K., Kasai, C., Aiba, Y., Onoda, H., Shisaka, Y., Sugimoto, H., Tosha, T., Kubo, M., Kamachi, T., Yoshizawa, K., Shoji, O. Catalytic oxidation of methane by wild-type cytochrome P450BM3 with chemically evolved decoy molecules. ACS Catal. 13, 8613-8623 (2023)
- Hragi, K., Nishide, A., Takagi, K., Iwai, K., Kim, M., Mizushima T., Structural insight into the recognition of the linear ubiquitin assembly complex by Shigella E3 ligase IpaH1.4/2.5. J. Biochem. 173, 317-326 (2023)
- Nishio, K., Kawarasaki, T., Sugiura, Y., Matsumoto, S., Konoshima, A., Takano, Y., Hayashi, M., Okumura, F., Kamura, T., Mizushima, T., Nakatsukasa, K. Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress. Sci. Adv. 9, eadf1956 (2023)
- Takeda, H., Shimba, K., Horitani, M., Kimura, T., Nomura, T., Kubo, M., Shiro, Y., Tosha, T. Trapping of a mononitrosyl nonheme intermediate of nitric oxide reductase by cryo-photolysis of caged nitric oxide. J. Phys. Chem. B 127, 846-854 (2023)(Selected for Cover Picture)
- Chongdar, N., Rodríguez-Maciá, P., Reijerse, E. J., Lubitz, W., Ogata, H., Birrell, J. A. Redox tuning of the H-cluster by second coordination sphere amino acids in the sensory [FeFe] hydrogenase from Thermotoga maritima. Chemical Science 14, 3682-3692 (2023)
2022年度
- Nishida, Y., Yanagisawa, S., Morita, R., Shigematsu, H., Shinzawa-Itoh, K., Yuki, S., Ogasawara, H., Shimuta, K., Iwamoto, T., Nakabayashi, C., Matsumura, W., Kato, H., Gopalasingam, C., Nagao, T., Qaqorh, T., Takahashi, Y., Yamazaki, S., Kamiya, K., Harada, R., Mizuno, N., Takahashi, H., Akeda, Y., Ohnishi, M., Ishii, Y., Kumasaka, T., Murata, T., Muramoto, K., Tosha, T., Shiro, Y., Honma, T., Shigeta, Y., Kubo, M., Takashima, S., Shintani, Y. Identifying antibiotics based on structural differences in the conserved allostery from mitochondrial heme-copper oxidases. Nat. Commun. 13, 7591 (2022)
- Yoshida, Y., Shimizu, I., Shimada, A., Nakahara, K., Yanagisawa, S., Kubo, M., Fukuda, S., Ishii, C., Yamamoto, H., Ishikawa, T., Kano, K., Aoki, J., Katsuumi, G., Suda, M., Ozaki, K., Yoshida, Y., Okuda, S., Ohta, S., Okamoto, S., Minokoshi, Y., Oda, K., Sasaoka, T., Abe, M., Sakimura, K., Kubota, Y., Yoshimura, N., Kajimura, S., Zuriaga, M., Walsh, K., Soga, T., Minamino, T. Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Sci. Rep. 12, 14883 (2022)
- Nagatomo, S., Shoji, M., Terada, T., Nakatani, K., Shigeta, Y., Hirota, S., Yanagisawa, S., Kubo, M., Kitagawa, T., Nagai, M., Ohki, M., Park, S.-Y., Shibayama, N. Heme-bound tyrosine vibrations in hemoglobin M: resonance Raman, crystallography and DFT calculation. Biophys. J. 121, 2767-2780 (2022)
- Hosaka, T., Nomura, T., Kubo, M., Nakane, T., Fangjia, L., Sekine, S., Ito, T., Murayama, K., Ihara, K., Ehara, H., Kashiwagi, K., Katsura, K., Akasaka, R., Hisano, T., Tanaka, T., Tanaka, R., Arima, T., Yamashita, A., Sugahara, M., Naitow, H., Matsuura, Y., Yoshizawa, S., Tono, K., Owada, S., Nureki, O., Kimura-Someya, T., Iwata, S., Nango, E., Shirouzu, M. Conformational alterations in unidirectional ion transport of a light-driven chloride pump revealed using X-ray free electron lasers. Proc. Natl. Acad. Sci. USA 119, e2117433119 (2022)
- Lucic, M., Wilson, M., Tosha, T., Sugimoto, H., Shilova, A., Axford, D., Owen, R., Hough, M., Worrall, J. Serial femtosecond crystallography reveals the role of water in the one- or two-electron redox chemistry of Compound I in the catalytic cycle of a B-type dye-decolorizing peroxidase DtpB ACS Catal. Vol. 12, 13349-13359 (2022)
- Moreno-Chicano, T., Carey, L., Axford, D., Beale, J., Doak, R., Duyvesteyn, H., Ebrahim, A., Henning, R., Monteiro, D., Myles, D., Owada, S., Sherrell, D., Straw, M., Srajer, V., Sugimoto, H., Tono, K., Tosha, T., Tews, I., Trebbin, M., Strange, R., Weiss, K., Worrall, J., Meilleur, F., Owen, R., Ghiladi, R., Hough, M. Complementarity of neutron, XFEL and synchrotron crystallography for defining the structures of metalloenzymes at room temperature. IUCrJ Vol. 9, 610-624 (2022)
- Rose, S., Baba, S., Okumura, H., Antonyuk, S., Sasaki, D., Hedison, T., Shanmugam, M., Heyes, D., Scrutton, N., Kumasaka, T., Tosha, T., Eady, R., Yamamoto, M., Hasnain, S. Single crystal spectroscopy and multiple structures from one crystal (MSOX) define catalysis in copper nitrite reductases. Proc. Natl. Acad. Sci. USA 119, e2205664119 (2022)
- Nakamura, H., Hisano, T., Rahman, M, Tosha, T., Shirouzu, M., Shiro, Y. Structural insight into heme detoxification by an ABC-type efflux pump in Gram-positive bacteria. Proc. Natll Acad. Sci. USA 119, e2123385119 (2022)
- Matsumura, H., Faponle, A., Hegedoorn, P.-L., Tosha, T., de Visser, S., Moënne-Loccoz, P. Mechanism of substrate inhibition in cytochrome-c dependent NO reductases from denitrifying bacteria (cNORs). J. Inorg. Biochem. 231, 111781 (2022)
- Kwon, H., Basran, J., Pathak, C., Hussain, M., Freeman, S., Fielding, A., Bailey, A., Stefanou, N., Sparkes, H., Tosha, T., Yamashita, K., Hirata, K., Murakami, H., Ueno, G., Ago, H., Tono, K., Yamamoto, M., Sawai, H., Shiro, Y., Sugimoto, H., Moody, P., Raven E. XFEL Crystal Structures of Peroxidase Compound II. Angew. Chem. Int. Ed. 60, 14578-14585 (2022)
- Stripp, S., Duffus, B. R., Fourmond, V., Léger, C., Leimkühler, S., Hirota, S., Hu, Y., Jasniewski, A., Ogata, H., Ribbe, M. W. Second and Outer Coordination Sphere Effects in Nitrogenase, Hydrogenase, Formate Dehydrogenase, and CO Dehydrogenase. Chemical Reviews 122, 11900-11973 (2022)
- Furlan, C., Chongdar, N., Gupta, P., Lubitz, W., Ogata, H., Blaza, J. N., Birrell, J. A. Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase. eLife 11, e79361 (2022)
2021年度
- Li, H., Nakajima, Y., Nomura, T., Sugahara, M., Yonekura, S., Chan, S. K., Nakane, T., Yamane, T., Umena, Y., Suzuki, M., Masuda, T., Motomura, T., Naitow, H., Matsuura, Y., Kimura, T., Tono, K., Owada, S., Joti, Y., Tanaka, R., Nango, E., Akita, F., Kubo, M., Iwata, S., Shen, J.-R., Suga, M. Capturing structural changes of photosystem II using time-resolved serial femtosecond crystallography with proper flash excitations. IUCrJ 8, 431-443 (2021).
- Nomura, T., Kimura, T., Kanematsu, Y., Yamada, D., Yamashita, K., Hirata, K., Ueno, G., Murakami, H., Hisano, T., Yamagiwa, R., Takeda, H., Gopalasingam, C., Kousaka, R., Yanagisawa, S., Shoji, O., Kumasaka, T., Yamamoto, M., Takano, Y., Sugimoto, H., Tosha, T., Kubo, M., Shiro, Y. Short-lived intermediate in N2O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography. Proc. Natl. Acad. Sci. USA Vol. 118, e2101481118 (2021).